MolNFT v1 · #163588 · protein
Native crystal structure of ergothioneine degrading enzyme ergothionase from treponema denticola
6S7J · Uncharacterized protein: “Native crystal structure of ergothioneine degrading enzyme ergothionase from treponema denticola”. X-ray diffraction, 20 pockets (best druggability 0.80). MolNFT v1 #163588 on GenesisL1: 3D structure…
- PDB
- 6S7J
- Type
- protein
- Length
- 3,973 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized protein
- UniProt
- M2BPW8
- Pockets
- 20 · best druggability 0.80
Structure
x-ray diffraction · 3 distinct chains · 60% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, D, E, G | Uncharacterized protein | protein | 497 | 59% helix, 7% strand | M2BPW8 |
| C | Uncharacterized protein | protein | 496 | 60% helix, 7% strand | M2BPW8 |
| F, H | Uncharacterized protein | protein | 496 | 60% helix, 7% strand | M2BPW8 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 128 | 0.80 | 0.98 | 42 | empty |
| 2 | 106 | 0.79 | 0.98 | 32 | empty |
| 3 | 101 | 0.78 | 0.98 | 30 | empty |
| 4 | 94 | 0.77 | 0.97 | 28 | empty |
| 5 | 90 | 0.77 | 0.98 | 31 | empty |
Interfaces
14 interfaces between chains.
- E–F · 3667 Ų buried · 58 hydrogen bonds · protein-protein
- G–H · 3663 Ų buried · 61 hydrogen bonds · protein-protein
- C–D · 3624 Ų buried · 58 hydrogen bonds · protein-protein
- A–B · 3612 Ų buried · 52 hydrogen bonds · protein-protein
- E–G · 3537 Ų buried · 53 hydrogen bonds · protein-protein
Compared structures
- 6S7J · Native crystal structure of ergothioneine degrading enzyme Ergothionase from Treponema… · the same entry in another collection · chain G against G, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt M2BPW8
- Elsewhere: RCSB PDB 6S7J · PDBe 6S7J · UniProt M2BPW8
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.