MolNFT v1 · #163574 · protein
Crystal structure of CARM1 in complex with inhibitor UM305
6S74: “Crystal structure of CARM1 in complex with inhibitor UM305”. X-ray diffraction, 1 ligand (KY8). MolNFT v1 #163574 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6S74
- Type
- protein
- Length
- 1,368 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q86X55
- Ligands
- KY8
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | — | protein | 342 | — | Q86X55 |
Ligands and binding sites
- KY8 · (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-[[3-azanylpropyl-[3-(pyrimidin-2-ylamino) propyl]amino]methyl]oxolane-3,4-diol · ligand · 4 copies · chains A, B, C, D
- GOL · Glycerol · additive · 3 copies · chains A, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6S74 · Crystal structure of CARM1 in complex with inhibitor UM305 · the same entry in another collection · chain D against D, TM-score 1.00
- Q86X55 · AlphaFold monomer V2.0 prediction for histone-arginine methyltransferase CARM1 (Q86X55) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q86X55
- Elsewhere: RCSB PDB 6S74 · PDBe 6S74 · UniProt Q86X55
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