MolNFT v1 · #163409 · protein

Crystal structure of human wild type sting in complex with 2'3'- cyclic-gmp-2'F-2'DAMP

6S27 · Stimulator of interferon protein: “Crystal structure of human wild type sting in complex with 2'3'- cyclic-gmp-2'F-2'DAMP”. X-ray diffraction, 1 ligand (KT8), 1 pocket (best druggability 0.36). MolNFT v1 #163409 on GenesisL1: 3D…

PDB: 6S27
Type: protein
Length: 172 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Stimulator of interferon protein
UniProt: A0A2R3XZB7
Ligands: KT8
Pockets: 1 · best druggability 0.36

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Stimulator of interferon protein	protein	172	40% helix, 27% strand	A0A2R3XZB7

Ligands and binding sites

KT8 · 2'3'-cyclic-GMP-2'F-2'dAMP · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	100	0.36	0.74	16	empty

Compared structures

6S27 · Crystal structure of human wild type STING in complex with 2'3'-cyclic-GMP-2'F-2'dAMP · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A2R3XZB7
Elsewhere: RCSB PDB 6S27 · PDBe 6S27 · UniProt A0A2R3XZB7

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