MolNFT v1 · #163386 · protein
Crystal structure of DYRK1A with small molecule inhibitor
6S1I: “Crystal structure of DYRK1A with small molecule inhibitor”. X-ray diffraction, 2 ligands (KR8, SO4). MolNFT v1 #163386 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6S1I
- Type
- protein
- Length
- 1,384 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q13627
- Ligands
- KR8, SO4
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 347 | — | Q13627 |
| B | — | protein | 346 | — | Q13627 |
| C | — | protein | 345 | — | Q13627 |
| D | — | protein | 346 | — | Q13627 |
Ligands and binding sites
- KR8 · ~{N}-methyl-~{N}-phenyl-4-pyrazolo[1,5-b]pyridazin-3-yl-pyrimidin-2-amine · ligand · 4 copies · chains A, B, C, D
- SO4 · Sulfate ion · ion · 7 copies · chains A, B, C, D
- PG4 · Tetraethylene glycol · additive · 5 copies · chains A, B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13627
- Elsewhere: RCSB PDB 6S1I · PDBe 6S1I · UniProt Q13627
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.