MolNFT v1 · #163373 · DNA

Pyridine derivative of the natural alkaloid berberine as human telomeric G-quadruplex binder

6S15: “Pyridine derivative of the natural alkaloid berberine as human telomeric G-quadruplex binder”. X-ray diffraction, 2 ligands (KQT, K). MolNFT v1 #163373 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6S15
Type: DNA
Length: 24 nucleotides
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Ligands: KQT, K

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	—	dna	12	—	—

Ligands and binding sites

KQT · Berberine · ligand · chains A, B
K · Potassium ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6S15 · Pyridine derivative of the natural alkaloid Berberine as Human Telomeric G-quadruplex… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 6S15 · PDBe 6S15

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.