MolNFT v1 · #163332 · protein
Structure of S-MGM1 decorating the outer surface of tubulated lipid membranes in the gtpgammas bound state
6RZU · Putative mitochondrial dynamin protein: “Structure of S-MGM1 decorating the outer surface of tubulated lipid membranes in the gtpgammas bound state”. Electron microscopy, 20 pockets (best druggability 0.80). MolNFT v1 #163332 on…
- PDB
- 6RZU
- Type
- protein
- Length
- 7,908 residues
- Chains
- 12
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative mitochondrial dynamin protein
- UniProt
- G0SGC7
- Pockets
- 20 · best druggability 0.80
Structure
electron microscopy · 1 distinct chain · 63% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F, G, H, I, J, K, L | Putative mitochondrial dynamin protein | protein | 659 | 63% helix, 7% strand | G0SGC7 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 223 | 0.80 | 0.93 | 53 | empty |
| 2 | 191 | 0.79 | 0.94 | 50 | empty |
| 3 | 169 | 0.76 | 0.92 | 45 | empty |
| 4 | 181 | 0.76 | 0.91 | 52 | empty |
| 5 | 82 | 0.74 | 0.96 | 23 | empty |
Interfaces
23 interfaces between chains.
- C–D · 673 Ų buried · 2 hydrogen bonds · protein-protein
- I–J · 669 Ų buried · 2 hydrogen bonds · protein-protein
- K–L · 667 Ų buried · 3 hydrogen bonds · protein-protein
- G–H · 659 Ų buried · 3 hydrogen bonds · protein-protein
- E–F · 653 Ų buried · 3 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 12 disulfide (disulfide).
Compared structures
- 6RZU · Structure of s-Mgm1 decorating the outer surface of tubulated lipid membranes in the… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G0SGC7
- Elsewhere: RCSB PDB 6RZU · PDBe 6RZU · UniProt G0SGC7
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