MolNFT v1 · #163075 · protein
Structure of the bateman module of human CNNM4.
6RS2 · Metal transporter CNNM4: “Structure of the bateman module of human CNNM4.”. X-ray diffraction, 4 pockets (best druggability 0.68). MolNFT v1 #163075 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6RS2
- Type
- protein
- Length
- 578 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Metal transporter CNNM4
- UniProt
- Q6P4Q7
- Pockets
- 4 · best druggability 0.68
Structure
x-ray diffraction · 3 distinct chains · 41% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B, A | Metal transporter CNNM4 | protein | 144 | 43% helix, 27% strand | Q6P4Q7 |
| C | Metal transporter CNNM4 | protein | 146 | 40% helix, 27% strand | Q6P4Q7 |
| D | Metal transporter CNNM4 | protein | 144 | 40% helix, 27% strand | Q6P4Q7 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 502 | 0.68 | 0.79 | 50 | empty |
| 2 | 539 | 0.68 | 0.78 | 48 | empty |
| 3 | 79 | 0.36 | 0.76 | 14 | empty |
| 4 | 61 | 0.34 | 0.77 | 18 | empty |
Interfaces
3 interfaces between chains.
- B–C · 1165 Ų buried · 2 hydrogen bonds · protein-protein
- D–A · 1117 Ų buried · 4 hydrogen bonds · protein-protein
- C–D · 130 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6P4Q7
- Elsewhere: RCSB PDB 6RS2 · PDBe 6RS2 · UniProt Q6P4Q7
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