MolNFT v1 · #163028 · protein

X-ray crystal structure of protiated (H) small monoclinic unit cell ca IX sv.

6RQN · Carbonic anhydrase 9: “X-ray crystal structure of protiated (H) small monoclinic unit cell ca IX sv.”. X-ray diffraction, 1 ligand (ZN), 2 pockets (best druggability 0.55). MolNFT v1 #163028 on GenesisL1: 3D structure, binding sites…

PDB: 6RQN
Type: protein
Length: 256 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Carbonic anhydrase 9
EC: 4.2.1.1
UniProt: Q16790
Ligands: ZN
Pockets: 2 · best druggability 0.55

Structure

x-ray diffraction · 1 distinct chain · 15% helix, 34% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Carbonic anhydrase 9 (EC 4.2.1.1)	protein	256	15% helix, 34% strand	Q16790

Ligands and binding sites

ZN · Zinc ion · metal · chains A
ACT · Acetate ion · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	191	0.55	0.79	23	ACT
2	61	0.38	0.79	16	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

6RQN · X-ray crystal structure of protiated (H) small monoclinic unit cell CA IX SV. · the same entry in another collection · chain A against A, TM-score 1.00
Q16790 · AlphaFold monomer V2.0 prediction for carbonic anhydrase 9 (Q16790) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q16790
Elsewhere: RCSB PDB 6RQN · PDBe 6RQN · UniProt Q16790

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.