E. COLI DNA gyrase - DNA binding and cleavage domain in state 1

Structure

electron microscopy · 4 distinct chains.

Ligands and binding sites

• JHN · (3~{R})-3-[[4-(3,4-dihydro-2~{H}-pyrano[2,3-c]pyridin-6-ylmethylamino)piperidin-1-yl]methyl]-1,4,7-triazatricyclo[6.3.1.0^{4,12}]dodeca-6,8(12),9-triene-5,11-dione · ligand · chains A, C, G, H

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 6RKU · E. coli DNA Gyrase - DNA binding and cleavage domain in State 1 · the same entry in another collection · chain H against H, TM-score 1.00
• P0AES4 · AlphaFold monomer V2.0 prediction for DNA gyrase subunit a (P0AES4) · a predicted model of the same protein · chain C against A, TM-score 0.96
• P0AES6 · AlphaFold monomer V2.0 prediction for DNA gyrase subunit B (P0AES6) · a predicted model of the same protein · chain D against A, TM-score 0.78

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P0AES4
• Every structure of UniProt P0AES6
• Elsewhere: RCSB PDB 6RKU · PDBe 6RKU · UniProt P0AES4 · UniProt P0AES6