MolNFT v1 · #162727 · protein

Structure of chloroflexus aggregans CAGG_3753 lov domain

6RHG · Multi-sensor hybrid histidine kinase: “Structure of chloroflexus aggregans CAGG_3753 lov domain”. X-ray diffraction, 1 ligand (FMN), 3 pockets (best druggability 0.72). MolNFT v1 #162727 on GenesisL1: 3D structure, binding sites and…

PDB: 6RHG
Type: protein
Length: 210 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Multi-sensor hybrid histidine kinase
UniProt: B8GAY9
Ligands: FMN
Pockets: 3 · best druggability 0.72

Structure

x-ray diffraction · 1 distinct chain · 26% helix, 38% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Multi-sensor hybrid histidine kinase	protein	105	26% helix, 38% strand	B8GAY9

Ligands and binding sites

FMN · Flavin mononucleotide · ligand · 2 copies · chains A, B
GOL · Glycerol · additive · 3 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	163	0.72	0.90	24	FMN
2	168	0.71	0.89	23	FMN
3	134	0.43	0.76	21	GOL

Interfaces

1 interface between chains.

A–B · 720 Å² buried · 6 hydrogen bonds · protein-protein

Compared structures

6RHG · Structure of Chloroflexus aggregans Cagg_3753 LOV domain · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B8GAY9
Elsewhere: RCSB PDB 6RHG · PDBe 6RHG · UniProt B8GAY9

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