MolNFT v1 · #162476 · protein
Ruminococcus gnavus sialic acid aldolase wild type
6RAB · Putative N-acetylneuraminate lyase: “Ruminococcus gnavus sialic acid aldolase wild type”. X-ray diffraction, 4 pockets (best druggability 0.70). MolNFT v1 #162476 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6RAB
- Type
- protein
- Length
- 602 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative N-acetylneuraminate lyase
- UniProt
- A7B555
- Pockets
- 4 · best druggability 0.70
Structure
x-ray diffraction · 1 distinct chain · 54% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Putative N-acetylneuraminate lyase | protein | 301 | 54% helix, 13% strand | A7B555 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 227 | 0.70 | 0.87 | 39 | empty |
| 2 | 406 | 0.68 | 0.80 | 38 | empty |
| 3 | 398 | 0.67 | 0.80 | 36 | empty |
| 4 | 61 | 0.28 | 0.74 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 1690 Ų buried · 18 hydrogen bonds · protein-protein
Compared structures
- 6RAB · Ruminococcus gnavus sialic acid aldolase Wild Type · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A7B555
- Elsewhere: RCSB PDB 6RAB · PDBe 6RAB · UniProt A7B555
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.