MolNFT v1 · #162363 · protein

Recombinantly produced KUSTA0087/KUSTA0088 complex, C32M/C101M mutant

6R6N · Small soluble cyt C: “Recombinantly produced KUSTA0087/KUSTA0088 complex, C32M/C101M mutant”. X-ray diffraction, 1 ligand (HEC), 2 pockets (best druggability 0.69). MolNFT v1 #162363 on GenesisL1: 3D structure, binding sites and…

PDB: 6R6N
Type: protein
Length: 211 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Small soluble cyt C; KUSTA0088
UniProt: Q1Q7P4, Q1Q7P3
Ligands: HEC
Pockets: 2 · best druggability 0.69

Structure

x-ray diffraction · 2 distinct chains · 64% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Small soluble cyt C	protein	111	78% helix, 0% strand	Q1Q7P4
B	KUSTA0088	protein	100	49% helix, 4% strand	Q1Q7P3

Ligands and binding sites

HEC · Heme C · ligand · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	218	0.69	0.85	31	HEC
2	204	0.65	0.83	22	HEC

Interfaces

1 interface between chains.

A–B · 1073 Å² buried · 27 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 cofactor (heme c attachment).

Compared structures

6R6N · Recombinantly produced Kusta0087/Kusta0088 Complex, C32M/C101M mutant · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q1Q7P4
Every structure of UniProt Q1Q7P3
Elsewhere: RCSB PDB 6R6N · PDBe 6R6N · UniProt Q1Q7P4 · UniProt Q1Q7P3

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.