MolNFT v1 · #162067 · protein

Cryo-EM structure of T7 bacteriophage portal protein, 12MER, open valve

6QXM: “Cryo-EM structure of T7 bacteriophage portal protein, 12MER, open valve”. Electron microscopy, 20 pockets (best druggability 0.84). MolNFT v1 #162067 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6QXM
Type: protein
Length: 4,704 residues
Chains: 12
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Portal protein
UniProt: P03728
Pockets: 20 · best druggability 0.84

Structure

electron microscopy · 1 distinct chain · 37% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D, E, F, G, H, I, J, K, L	Portal protein	protein	392	37% helix, 13% strand	P03728

Pockets

20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	971	0.84	0.85	127	empty
2	988	0.84	0.85	136	empty
3	1129	0.83	0.84	128	empty
4	993	0.83	0.84	111	empty
5	1073	0.83	0.84	123	empty

Interfaces

24 interfaces between chains.

D–E · 3252 Å² buried · 24 hydrogen bonds · protein-protein
J–K · 3238 Å² buried · 24 hydrogen bonds · protein-protein
A–L · 3235 Å² buried · 22 hydrogen bonds · protein-protein
E–F · 3234 Å² buried · 26 hydrogen bonds · protein-protein
G–H · 3232 Å² buried · 25 hydrogen bonds · protein-protein

Compared structures

6QXM · Cryo-EM structure of T7 bacteriophage portal protein, 12mer, open valve · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P03728
Elsewhere: RCSB PDB 6QXM · PDBe 6QXM · UniProt P03728

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.