MolNFT v1 · #161696 · protein
Small molecule inhibitor of the KEAP1-NRF2 protein-protein interaction
6QME: “Small molecule inhibitor of the KEAP1-NRF2 protein-protein interaction”. X-ray diffraction, 2 ligands (J6Q, SO4). MolNFT v1 #161696 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6QME
- Type
- protein
- Length
- 290 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q9Z2X8
- Ligands
- J6Q, SO4
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 290 | — | Q9Z2X8 |
Ligands and binding sites
- J6Q · (3~{S})-3-(4-chloranyl-3-methyl-phenyl)-3-(1-methylbenzotriazol-5-yl)propanoic acid · ligand · chains A
- SO4 · Sulfate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6QME · Small molecule inhibitor of the KEAP1-NRF2 protein-protein interaction · the same entry in another collection · chain A against A, TM-score 1.00
- Q9Z2X8 · AlphaFold monomer V2.0 prediction for kelch-like ech-associated protein 1 (Q9Z2X8) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Z2X8
- Elsewhere: RCSB PDB 6QME · PDBe 6QME · UniProt Q9Z2X8
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