MolNFT v1 · #161590 · protein
The structure of trehalose-6-phosphatase from burkholderia pseudomallei
6QJ6 · Trehalose 6-phosphate phosphatase: “The structure of trehalose-6-phosphatase from burkholderia pseudomallei”. X-ray diffraction, 2 ligands (MG, CL), 4 pockets (best druggability 0.76). MolNFT v1 #161590 on GenesisL1: 3D structure…
- PDB
- 6QJ6
- Type
- protein
- Length
- 519 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Trehalose 6-phosphate phosphatase
- EC
- 3.1.3.12
- UniProt
- Q63SB3
- Ligands
- MG, CL
- Pockets
- 4 · best druggability 0.76
Structure
x-ray diffraction · 2 distinct chains · 37% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Trehalose 6-phosphate phosphatase (EC 3.1.3.12) | protein | 265 | 36% helix, 22% strand | Q63SB3 |
| E | Trehalose 6-phosphate phosphatase (EC 3.1.3.12) | protein | 254 | 38% helix, 22% strand | Q63SB3 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 180 | 0.76 | 0.92 | 37 | MG |
| 2 | 331 | 0.52 | 0.74 | 38 | MG |
| 3 | 153 | 0.44 | 0.75 | 33 | empty |
| 4 | 63 | 0.26 | 0.71 | 14 | empty |
Interfaces
1 interface between chains.
- A–E · 626 Ų buried · 14 hydrogen bonds · protein-protein
Compared structures
- 6QJ6 · The structure of Trehalose-6-phosphatase from Burkholderia pseudomallei · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q63SB3
- Elsewhere: RCSB PDB 6QJ6 · PDBe 6QJ6 · UniProt Q63SB3
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.