MolNFT v1 · #161587 · protein
Crystal structure of the C. thermophilum condensin YCS4-BRN1 subcomplex
6QJ3 · Condensin complex subunit 1,CONDENSIN complex subunit 1…: “Crystal structure of the C. thermophilum condensin YCS4-BRN1 subcomplex”. X-ray diffraction, 9 pockets (best druggability 0.85). MolNFT v1 #161587 on GenesisL1: 3D…
- PDB
- 6QJ3
- Type
- protein
- Length
- 1,056 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Condensin complex subunit 1,CONDENSIN complex subunit 1, YCS4; Condensin complex subunit…
- UniProt
- G0SB82, G0SBJ6
- Pockets
- 9 · best druggability 0.85
Structure
x-ray diffraction · 3 distinct chains · 65% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Condensin complex subunit 1,CONDENSIN complex subunit 1, YCS4 | protein | 980 | 68% helix, 0% strand | G0SB82 |
| B | Condensin complex subunit 2 | protein | 56 | 21% helix, 7% strand | G0SBJ6 |
| C | BRN1 | protein | 20 | 0% helix, 0% strand | — |
Pockets
9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 944 | 0.85 | 0.86 | 113 | empty |
| 2 | 739 | 0.76 | 0.81 | 81 | empty |
| 3 | 535 | 0.68 | 0.78 | 65 | empty |
| 4 | 173 | 0.59 | 0.82 | 35 | empty |
| 5 | 247 | 0.57 | 0.78 | 33 | empty |
Interfaces
2 interfaces between chains.
- A–B · 2530 Ų buried · 15 hydrogen bonds · protein-protein
- A–C · 357 Ų buried · 1 hydrogen bond · protein-protein
Modifications
Observed in the structure: 31 modified (engineered).
Compared structures
- 6QJ3 · Crystal structure of the C. thermophilum condensin Ycs4-Brn1 subcomplex · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G0SB82
- Every structure of UniProt G0SBJ6
- Elsewhere: RCSB PDB 6QJ3 · PDBe 6QJ3 · UniProt G0SB82 · UniProt G0SBJ6
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