MolNFT v1 · #161571 · protein
Structure of ATPIP2;4
6QIM · Probable aquaporin PIP2-4: “Structure of ATPIP2;4”. X-ray diffraction, 4 pockets (best druggability 0.61). MolNFT v1 #161571 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6QIM
- Type
- protein
- Length
- 487 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Probable aquaporin PIP2-4
- UniProt
- Q9FF53
- Pockets
- 4 · best druggability 0.61
Structure
x-ray diffraction · 2 distinct chains · 68% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Probable aquaporin PIP2-4 | protein | 243 | 66% helix, 5% strand | Q9FF53 |
| B | Probable aquaporin PIP2-4 | protein | 244 | 69% helix, 1% strand | Q9FF53 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 372 | 0.61 | 0.77 | 39 | empty |
| 2 | 406 | 0.60 | 0.76 | 52 | empty |
| 3 | 167 | 0.49 | 0.77 | 24 | empty |
| 4 | 64 | 0.30 | 0.73 | 12 | empty |
Interfaces
1 interface between chains.
- A–B · 1524 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9FF53
- Elsewhere: RCSB PDB 6QIM · PDBe 6QIM · UniProt Q9FF53
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