MolNFT v1 · #161545 · protein
Structure of the mitogen activated kinase kinase 7 in complex with pyrazolopyrimidine 1M
6QHR: “Structure of the mitogen activated kinase kinase 7 in complex with pyrazolopyrimidine 1M”. X-ray diffraction, 1 ligand (J3N). MolNFT v1 #161545 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6QHR
- Type
- protein
- Length
- 286 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O14733
- Ligands
- J3N
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 286 | — | O14733 |
Ligands and binding sites
- J3N · 1-[(3~{R})-3-[4-azanyl-3-(1~{H}-pyrrolo[2,3-b]pyridin-5-yl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6QHR · Structure of the mitogen activated kinase kinase 7 in complex with pyrazolopyrimidine 1m · the same entry in another collection · chain A against A, TM-score 1.00
- O14733 · AlphaFold monomer V2.0 prediction for dual specificity mitogen- activated protein kinase… · a predicted model of the same protein · chain A against A, TM-score 0.90
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O14733
- Elsewhere: RCSB PDB 6QHR · PDBe 6QHR · UniProt O14733
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