MolNFT v1 · #161356 · protein
Structure of the core domaine of KNR4, an intrinsically disordered protein from saccharomyces cerevisiae - mutant S203A
6QBO · Cell wall assembly regulator SMI1: “Structure of the core domaine of KNR4, an intrinsically disordered protein from saccharomyces cerevisiae…”. X-ray diffraction, 5 pockets (best druggability 0.62). MolNFT v1 #161356 on GenesisL1…
- PDB
- 6QBO
- Type
- protein
- Length
- 439 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cell wall assembly regulator SMI1
- UniProt
- P32566
- Pockets
- 5 · best druggability 0.62
Structure
x-ray diffraction · 2 distinct chains · 39% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cell wall assembly regulator SMI1 | protein | 220 | 40% helix, 20% strand | P32566 |
| B | Cell wall assembly regulator SMI1 | protein | 219 | 38% helix, 20% strand | P32566 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 548 | 0.62 | 0.74 | 60 | empty |
| 2 | 228 | 0.51 | 0.76 | 29 | empty |
| 3 | 95 | 0.44 | 0.79 | 22 | empty |
| 4 | 126 | 0.40 | 0.75 | 21 | empty |
| 5 | 82 | 0.40 | 0.78 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 576 Ų buried · 11 hydrogen bonds · protein-protein
Compared structures
- 6QBO · structure of the core domaine of Knr4, an intrinsically disordered protein from… · the same entry in another collection · chain A against A, TM-score 1.00
- P32566 · AlphaFold monomer V2.0 prediction for cell wall assembly regulator SMI1 (P32566) · a predicted model of the same protein · chain B against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P32566
- Elsewhere: RCSB PDB 6QBO · PDBe 6QBO · UniProt P32566
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