MolNFT v1 · #161195 · protein

Antarctic fish cytoglobin 1 from D.MAWSONI

6Q6P: “Antarctic fish cytoglobin 1 from D.MAWSONI”. X-ray diffraction, 1 ligand (HEM), 4 pockets (best druggability 0.70). MolNFT v1 #161195 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6Q6P
Type: protein
Length: 313 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cytoglobin
UniProt: A0A192X9K5
Ligands: HEM
Pockets: 4 · best druggability 0.70

Structure

x-ray diffraction · 2 distinct chains · 77% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cytoglobin	protein	156	78% helix, 0% strand	A0A192X9K5
B	Cytoglobin	protein	157	76% helix, 0% strand	A0A192X9K5

Ligands and binding sites

HEM · Protoporphyrin IX containing Fe · ligand · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	218	0.70	0.86	27	HEM
2	194	0.69	0.86	25	HEM
3	106	0.41	0.76	31	empty
4	59	0.39	0.80	16	empty

Interfaces

1 interface between chains.

A–B · 265 Å² buried · 4 hydrogen bonds · protein-protein

Compared structures

6Q6P · Antarctic fish cytoglobin 1 from D.mawsoni · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A192X9K5
Elsewhere: RCSB PDB 6Q6P · PDBe 6Q6P · UniProt A0A192X9K5

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