MolNFT v1 · #161101 · protein
Structure of PROTEASE1 from pyrococcus horikoshii at room temperature in chipx microfluidic device
6Q3T · Deglycase PH1704: “Structure of PROTEASE1 from pyrococcus horikoshii at room temperature in chipx microfluidic device”. X-ray diffraction, 3 pockets (best druggability 0.56). MolNFT v1 #161101 on GenesisL1: 3D structure, binding…
- PDB
- 6Q3T
- Type
- protein
- Length
- 498 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Deglycase PH1704
- EC
- 3.5.1.124, 3.4.22.-
- UniProt
- O59413
- Pockets
- 3 · best druggability 0.56
Structure
x-ray diffraction · 1 distinct chain · 39% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | Deglycase PH1704 (EC 3.5.1.124, 3.4.22.-) | protein | 166 | 39% helix, 25% strand | O59413 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 179 | 0.56 | 0.81 | 29 | empty |
| 2 | 103 | 0.38 | 0.75 | 15 | empty |
| 3 | 80 | 0.37 | 0.76 | 15 | empty |
Interfaces
2 interfaces between chains.
- A–B · 874 Ų buried · 19 hydrogen bonds · protein-protein
- B–C · 767 Ų buried · 15 hydrogen bonds · protein-protein
Compared structures
- 6Q3T · Structure of Protease1 from Pyrococcus horikoshii at room temperature in ChipX… · the same entry in another collection · chain A against A, TM-score 1.00
- O59413 · AlphaFold monomer V2.0 prediction for deglycase PH1704 (O59413) · a predicted model of the same protein · chain B against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O59413
- Elsewhere: RCSB PDB 6Q3T · PDBe 6Q3T · UniProt O59413
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