MolNFT v1 · #160969 · protein

Crystal structure of caspase-1 in complex with vx-765

6PZP: “Crystal structure of caspase-1 in complex with vx-765”. X-ray diffraction, 1 ligand (P7S). MolNFT v1 #160969 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6PZP
Type: protein
Length: 262 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P29466
Ligands: P7S

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	174	—	P29466
B	—	protein	88	—	P29466

Ligands and binding sites

P7S · N-(4-amino-3-chlorobenzene-1-carbonyl)-3-methyl-L-valyl-N-[(2S)-1-carboxy-3-oxopropan-2-yl]-L-prolinamide · ligand · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6PZP · Crystal structure of caspase-1 in complex with VX-765 · the same entry in another collection · chain A against A, TM-score 1.00
P29466 · AlphaFold monomer V2.0 prediction for caspase-1 (P29466) · a predicted model of the same protein · chain B against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P29466
Elsewhere: RCSB PDB 6PZP · PDBe 6PZP · UniProt P29466

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