MolNFT v1 · #160713 · protein
Antibody scfv-M204 trimeric state
6PSC · Scfv-M204 antibody: “Antibody scfv-M204 trimeric state”. X-ray diffraction, 8 pockets (best druggability 0.65). MolNFT v1 #160713 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6PSC
- Type
- protein
- Length
- 675 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Scfv-M204 antibody
- Pockets
- 8 · best druggability 0.65
Structure
x-ray diffraction · 1 distinct chain · 4% helix, 52% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | Scfv-M204 antibody | protein | 225 | 4% helix, 52% strand | — |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 54 | 0.65 | 0.95 | 20 | empty |
| 2 | 205 | 0.54 | 0.78 | 35 | empty |
| 3 | 183 | 0.54 | 0.79 | 35 | empty |
| 4 | 119 | 0.40 | 0.76 | 23 | empty |
| 5 | 104 | 0.36 | 0.74 | 19 | empty |
Interfaces
2 interfaces between chains.
- B–C · 729 Ų buried · 9 hydrogen bonds · protein-protein
- A–C · 384 Ų buried · 1 hydrogen bond · protein-protein
Modifications
Observed in the structure: 6 disulfide (disulfide).
Compared structures
- 6PSC · Antibody scFv-M204 trimeric state · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6PSC · PDBe 6PSC
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