MolNFT v1 · #160712 · protein
Crystal structure of BRD4 bromodomain 1 with N-methylpyrrolidin-2-one (nmp) derivative 18 (5-{[(3R)-1-methyl-5-oxopyrrolidin-3-YL]METHYL}- 2,3,4,5-tetrahydro-1H-PYRIDO[4,3-B]INDOL-1-one)
6PSB: “Crystal structure of BRD4 bromodomain 1 with N-methylpyrrolidin-2-one (nmp) derivative 18…”. X-ray diffraction, 1 ligand (Y18). MolNFT v1 #160712 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6PSB
- Type
- protein
- Length
- 125 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O60885
- Ligands
- Y18
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 125 | — | O60885 |
Ligands and binding sites
- Y18 · 5-{[(3R)-1-methyl-5-oxopyrrolidin-3-yl]methyl}-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6PSB · Crystal structure of BRD4 bromodomain 1 with N-methylpyrrolidin-2-one (NMP) derivative 18… · the same entry in another collection · chain A against A, TM-score 1.00
- O60885 · AlphaFold monomer V2.0 prediction for bromodomain-containing protein 4 (O60885) · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O60885
- Elsewhere: RCSB PDB 6PSB · PDBe 6PSB · UniProt O60885
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