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MolNFT v1 · #160580 · RNA

Cryo-EM structure of the full-length bacillus subtilis glyqs T-box riboswitch in complex with tRNA-gly

6POM · T-box glyqs leader (155-mer): “Cryo-EM structure of the full-length bacillus subtilis glyqs T-box riboswitch in complex with tRNA-gly”. Electron microscopy, 12 pockets (best druggability 0.65). MolNFT v1 #160580 on GenesisL1: 3D…

PDB
6POM
Type
RNA
Length
230 nucleotides
Chains
2
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
T-box glyqs leader (155-mer); Trnagly (75-mer)
Pockets
12 · best druggability 0.65

Structure

electron microscopy · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
AT-box glyqs leader (155-mer)rna155——
BTrnagly (75-mer)rna75——

Pockets

12 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
17260.650.7533empty
27670.640.7442empty
34460.630.7823empty
46000.630.7637empty
55200.630.7628empty

Interfaces

1 interface between chains.

  • A–B · 1136 Ų buried · 48 hydrogen bonds · nucleic-nucleic

Compared structures

  • 6POM · Cryo-EM structure of the full-length Bacillus subtilis glyQS T-box riboswitch in complex… · the same entry in another collection · chain A against A, TM-score 1.00

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