MolNFT v1 · #160307 · protein
Pirf geranyltransferase
6PGM: “Pirf geranyltransferase”. X-ray diffraction, 6 pockets (best druggability 0.75). MolNFT v1 #160307 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6PGM
- Type
- protein
- Length
- 582 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Pirf geranyltransferase
- EC
- 2.-.-.-
- UniProt
- J3S802
- Pockets
- 6 · best druggability 0.75
Structure
x-ray diffraction · 1 distinct chain · 44% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Pirf geranyltransferase (EC 2.-.-.-) | protein | 291 | 44% helix, 30% strand | J3S802 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 511 | 0.75 | 0.83 | 53 | empty |
| 2 | 541 | 0.72 | 0.81 | 61 | empty |
| 3 | 159 | 0.47 | 0.76 | 23 | empty |
| 4 | 67 | 0.44 | 0.81 | 12 | empty |
| 5 | 118 | 0.39 | 0.75 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 1381 Ų buried · 24 hydrogen bonds · protein-protein
Compared structures
- 6PGM · PirF geranyltransferase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt J3S802
- Elsewhere: RCSB PDB 6PGM · PDBe 6PGM · UniProt J3S802
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