MolNFT v1 · #160278 · protein
RSEGFP2 with a chlorinated chromophore in the fluorescent on-state
6PFR · Green fluorescent protein: “RSEGFP2 with a chlorinated chromophore in the fluorescent on-state”. X-ray diffraction, 1 ligand (OHD), 1 pocket (best druggability 0.74). MolNFT v1 #160278 on GenesisL1: 3D structure, binding sites and…
- PDB
- 6PFR
- Type
- protein
- Length
- 239 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Green fluorescent protein
- Ligands
- OHD
- Pockets
- 1 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 15% helix, 49% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Green fluorescent protein | protein | 239 | 15% helix, 49% strand | — |
Ligands and binding sites
- OHD · {(4Z)-2-[(1S)-1-aminoethyl]-4-[(3-chloro-4-hydroxyphenyl)methylidene]-5-oxo-4,5-dihydro-1H-imidazol-1-yl}acetic acid · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 80 | 0.74 | 0.97 | 25 | OHD |
Modifications
Observed in the structure: 2 covalent (covalent ligand).
Compared structures
- 6PFR · rsEGFP2 with a chlorinated chromophore in the fluorescent on-state · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6PFR · PDBe 6PFR
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