MolNFT v1 · #160228 · protein
Crystal structure of human nampt in complex with nvp-LTM976
6PEB: “Crystal structure of human nampt in complex with nvp-LTM976”. X-ray diffraction, 2 ligands (OE4, PO4). MolNFT v1 #160228 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6PEB
- Type
- protein
- Length
- 1,877 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P43490
- Ligands
- OE4, PO4
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 469 | — | P43490 |
| B | — | protein | 468 | — | P43490 |
| C | — | protein | 469 | — | P43490 |
| D | — | protein | 471 | — | P43490 |
Ligands and binding sites
- OE4 · N-{4-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl) methyl]phenyl}-3-(pyridin-3-yl)azetidine-1-carboxamide · ligand · 3 copies · chains A, B, C, D
- PO4 · Phosphate ion · ion · 12 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6PEB · Crystal Structure of human NAMPT in complex with NVP-LTM976 · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P43490
- Elsewhere: RCSB PDB 6PEB · PDBe 6PEB · UniProt P43490
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