MolNFT v1 · #159861 · protein

Crystal structure of ketosteroid isomerase from mycobacterium hassiacum (mhksi)

6P3L · Snoal-like domain protein: “Crystal structure of ketosteroid isomerase from mycobacterium hassiacum (mhksi)”. X-ray diffraction, 2 ligands (GAI, SO4), 3 pockets (best druggability 0.61). MolNFT v1 #159861 on GenesisL1: 3D structure…

PDB: 6P3L
Type: protein
Length: 230 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Snoal-like domain protein
EC: 5.3.3.1
UniProt: K5BJ73
Ligands: GAI, SO4
Pockets: 3 · best druggability 0.61

Structure

x-ray diffraction · 1 distinct chain · 32% helix, 41% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Snoal-like domain protein (EC 5.3.3.1)	protein	115	32% helix, 41% strand	K5BJ73

Ligands and binding sites

GAI · Guanidine · ligand · 2 copies · chains A, B
SO4 · Sulfate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	179	0.61	0.82	28	empty
2	126	0.55	0.82	20	empty
3	75	0.39	0.79	19	empty

Interfaces

1 interface between chains.

A–B · 872 Å² buried · 15 hydrogen bonds · protein-protein

Compared structures

6P3L · Crystal Structure of Ketosteroid Isomerase from Mycobacterium hassiacum (mhKSI) · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt K5BJ73
Elsewhere: RCSB PDB 6P3L · PDBe 6P3L · UniProt K5BJ73

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.