MolNFT v1 · #159856 · protein
Mobile loops and electrostatic interactions maintain the flexible lambda tail tube
6P3E · Tail tube protein: “Mobile loops and electrostatic interactions maintain the flexible lambda tail tube”. Electron microscopy, 20 pockets (best druggability 0.75). MolNFT v1 #159856 on GenesisL1: 3D structure, binding sites and…
- PDB
- 6P3E
- Type
- protein
- Length
- 4,428 residues
- Chains
- 18
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tail tube protein
- UniProt
- P03733
- Pockets
- 20 · best druggability 0.75
Structure
electron microscopy · 1 distinct chain · 4% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R | Tail tube protein | protein | 246 | 4% helix, 30% strand | P03733 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 645 | 0.75 | 0.81 | 95 | empty |
| 2 | 394 | 0.75 | 0.85 | 57 | empty |
| 3 | 440 | 0.75 | 0.84 | 62 | empty |
| 4 | 434 | 0.75 | 0.84 | 64 | empty |
| 5 | 462 | 0.75 | 0.83 | 61 | empty |
Interfaces
42 interfaces between chains.
- B–C · 1651 Ų buried · 46 hydrogen bonds · protein-protein
- J–K · 1651 Ų buried · 46 hydrogen bonds · protein-protein
- O–P · 1648 Ų buried · 44 hydrogen bonds · protein-protein
- C–D · 1647 Ų buried · 44 hydrogen bonds · protein-protein
- D–E · 1647 Ų buried · 46 hydrogen bonds · protein-protein
Compared structures
- 6P3E · Mobile loops and electrostatic interactions maintain the flexible lambda tail tube · the same entry in another collection · chain D against D, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03733
- Elsewhere: RCSB PDB 6P3E · PDBe 6P3E · UniProt P03733
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.