MolNFT v1 · #159831 · protein
Structure of mouse ketohexokinase-C in complex with fructose and ADP
6P2D: “Structure of mouse ketohexokinase-C in complex with fructose and ADP”. X-ray diffraction, 2 ligands (ADP, FRU), 2 pockets (best druggability 0.72). MolNFT v1 #159831 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6P2D
- Type
- protein
- Length
- 296 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ketohexokinase
- UniProt
- A0A0J9YU79
- Ligands
- ADP, FRU
- Pockets
- 2 · best druggability 0.72
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ketohexokinase | protein | 296 | 38% helix, 24% strand | A0A0J9YU79 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 548 | 0.72 | 0.81 | 57 | FRU, ADP |
| 2 | 57 | 0.34 | 0.78 | 13 | empty |
Compared structures
- 6P2D · Structure of mouse ketohexokinase-C in complex with fructose and ADP · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0J9YU79
- Elsewhere: RCSB PDB 6P2D · PDBe 6P2D · UniProt A0A0J9YU79
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