MolNFT v1 · #15983 · protein
Solution structure of switch arc, a mutant with 3(10) helices replacing a wild-type beta-ribbon
1NLA · Transcriptional repressor arc: “Solution structure of switch arc, a mutant with 3(10) helices replacing a wild-type beta-ribbon”. Solution nmr, 3 pockets (best druggability 0.34). MolNFT v1 #15983 on GenesisL1: 3D structure, binding…
- PDB
- 1NLA
- Type
- protein
- Length
- 106 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcriptional repressor arc
- UniProt
- P03050
- Pockets
- 3 · best druggability 0.34
Structure
solution nmr · 1 distinct chain · 64% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Transcriptional repressor arc | protein | 53 | 64% helix, 0% strand | P03050 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 76 | 0.34 | 0.75 | 14 | empty |
| 2 | 51 | 0.34 | 0.78 | 11 | empty |
| 3 | 85 | 0.31 | 0.73 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 1244 Ų buried · 11 hydrogen bonds · protein-protein
Compared structures
- 1NLA · Solution Structure of Switch Arc, a Mutant with 3(10) Helices Replacing a Wild-Type… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03050
- Elsewhere: RCSB PDB 1NLA · PDBe 1NLA · UniProt P03050
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