MolNFT v1 · #159794 · protein

Transcription antitermination factor Q21

6P1B · Q protein: “Transcription antitermination factor Q21”. X-ray diffraction, 1 ligand (CL), 3 pockets (best druggability 0.65). MolNFT v1 #159794 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6P1B
Type: protein
Length: 296 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Q protein
UniProt: Q9XJQ6
Ligands: CL
Pockets: 3 · best druggability 0.65

Structure

x-ray diffraction · 2 distinct chains · 69% helix, 7% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Q protein	protein	150	67% helix, 7% strand	Q9XJQ6
B	Q protein	protein	146	71% helix, 7% strand	Q9XJQ6

Ligands and binding sites

CL · Chloride ion · ion · 9 copies · chains A, B
EDO · 1,2-ethanediol · additive · 4 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	521	0.65	0.76	42	empty
2	176	0.48	0.77	26	empty
3	65	0.29	0.73	16	empty

Interfaces

1 interface between chains.

A–B · 300 Å² buried · 4 hydrogen bonds · protein-protein

Compared structures

6P1B · Transcription antitermination factor Q21 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9XJQ6
Elsewhere: RCSB PDB 6P1B · PDBe 6P1B · UniProt Q9XJQ6

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