MolNFT v1 · #159588 · protein
Structure of drug-resistant V27A mutant of the influenza M2 proton channel bound to spiroadamantyl amine inhibitor, tm + cytosolic helix construct
6OUG: “Structure of drug-resistant V27A mutant of the influenza M2 proton channel bound to spiroadamantyl amine…”. X-ray diffraction, 1 ligand (E01). MolNFT v1 #159588 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6OUG
- Type
- protein
- Length
- 273 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q3YPZ4
- Ligands
- E01
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 35 | — | Q3YPZ4 |
| B | — | protein | 33 | — | Q3YPZ4 |
| C, D, E, F, G | — | protein | 34 | — | Q3YPZ4 |
| H | — | protein | 35 | — | Q3YPZ4 |
Ligands and binding sites
- E01 · (1r,1'S,3'S,5'S,7'S)-spiro[cyclohexane-1,2'-tricyclo[3.3.1.1~3,7~]decan]-4-amine · ligand · 2 copies · chains A, B, C, D, E, F, G, H
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6OUG · Structure of drug-resistant V27A mutant of the influenza M2 proton channel bound to… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q3YPZ4
- Elsewhere: RCSB PDB 6OUG · PDBe 6OUG · UniProt Q3YPZ4
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