MolNFT v1 · #159296 · protein
Cdtb double heptamer long form mask 3 modeled from cryo-EM MAP reconstructed using C7 symmetry
6OKU · ADP-ribosyltransferase binding component: “Cdtb double heptamer long form mask 3 modeled from cryo-EM MAP reconstructed using C7 symmetry”. Electron microscopy, 20 pockets (best druggability 0.79). MolNFT v1 #159296 on GenesisL1: 3D…
- PDB
- 6OKU
- Type
- protein
- Length
- 3,451 residues
- Chains
- 7
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- ADP-ribosyltransferase binding component
- UniProt
- A8DS70
- Pockets
- 20 · best druggability 0.79
Structure
electron microscopy · 1 distinct chain · 11% helix, 36% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F, G | ADP-ribosyltransferase binding component | protein | 493 | 11% helix, 36% strand | A8DS70 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 940 | 0.79 | 0.81 | 117 | empty |
| 2 | 701 | 0.78 | 0.83 | 83 | empty |
| 3 | 1137 | 0.77 | 0.79 | 117 | empty |
| 4 | 105 | 0.77 | 0.97 | 29 | empty |
| 5 | 98 | 0.76 | 0.97 | 24 | empty |
Interfaces
7 interfaces between chains.
- A–B · 2404 Ų buried · 40 hydrogen bonds · protein-protein
- C–D · 2386 Ų buried · 40 hydrogen bonds · protein-protein
- D–E · 2385 Ų buried · 36 hydrogen bonds · protein-protein
- F–G · 2369 Ų buried · 37 hydrogen bonds · protein-protein
- B–C · 2363 Ų buried · 40 hydrogen bonds · protein-protein
Compared structures
- 6OKU · CDTb Double Heptamer Long Form Mask 3 Modeled from Cryo-EM Map Reconstructed using C7… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A8DS70
- Elsewhere: RCSB PDB 6OKU · PDBe 6OKU · UniProt A8DS70
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