MolNFT v1 · #159203 · protein

Structure of compound 4 bound human phospholipase D2 catalytic domain

6OHQ: “Structure of compound 4 bound human phospholipase D2 catalytic domain”. X-ray diffraction, 2 ligands (MKA, SO4). MolNFT v1 #159203 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6OHQ
Type: protein
Length: 1,157 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: O14939
Ligands: MKA, SO4

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	580	—	O14939
B	—	protein	577	—	O14939

Ligands and binding sites

MKA · 4-fluoro-N-{(2S)-1-[4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidin-1-yl]propan-2-yl}benzamide · ligand · 2 copies · chains A, B
SO4 · Sulfate ion · ion · 24 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6OHQ · Structure of compound 4 bound human Phospholipase D2 catalytic domain · the same entry in another collection · chain A against A, TM-score 1.00
O14939 · AlphaFold monomer V2.0 prediction for phospholipase D2 (O14939) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O14939
Elsewhere: RCSB PDB 6OHQ · PDBe 6OHQ · UniProt O14939

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