MolNFT v1 · #159101 · protein
Structure of cagx from a cryo-EM reconstruction of a T4SS
6OEG · Type IV secretion system apparatus protein cagx: “Structure of cagx from a cryo-EM reconstruction of a T4SS”. Electron microscopy, 20 pockets (best druggability 0.62). MolNFT v1 #159101 on GenesisL1: 3D structure, binding sites and…
- PDB
- 6OEG
- Type
- protein
- Length
- 2,268 residues
- Chains
- 14
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Type IV secretion system apparatus protein cagx
- UniProt
- A0A2J9KJM4
- Pockets
- 20 · best druggability 0.62
Structure
electron microscopy · 1 distinct chain · 23% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a | Type IV secretion system apparatus protein cagx | protein | 162 | 23% helix, 23% strand | A0A2J9KJM4 |
Pockets
20 pockets found on a 1 Å grid, 14 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 411 | 0.62 | 0.77 | 47 | empty |
| 2 | 349 | 0.58 | 0.76 | 33 | empty |
| 3 | 317 | 0.57 | 0.76 | 37 | empty |
| 4 | 370 | 0.57 | 0.75 | 39 | empty |
| 5 | 322 | 0.56 | 0.76 | 35 | empty |
Interfaces
14 interfaces between chains.
- R–S · 518 Ų buried · 3 hydrogen bonds · protein-protein
- V–W · 461 Ų buried · 2 hydrogen bonds · protein-protein
- X–Y · 456 Ų buried · 2 hydrogen bonds · protein-protein
- V–a · 450 Ų buried · 2 hydrogen bonds · protein-protein
- N–a · 450 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
- 6OEG · Structure of CagX from a cryo-EM reconstruction of a T4SS · the same entry in another collection · chain N against N, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A2J9KJM4
- Elsewhere: RCSB PDB 6OEG · PDBe 6OEG · UniProt A0A2J9KJM4
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