MolNFT v1 · #158861 · protein

Crystal structure of CSM6 H132A mutant

6O6T: “Crystal structure of CSM6 H132A mutant”. X-ray diffraction, 9 pockets (best druggability 0.87). MolNFT v1 #158861 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6O6T
Type: protein
Length: 865 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: CSM6
UniProt: B6YWC3
Pockets: 9 · best druggability 0.87

Structure

x-ray diffraction · 2 distinct chains · 47% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	CSM6	protein	433	48% helix, 21% strand	B6YWC3
B	CSM6	protein	432	46% helix, 19% strand	B6YWC3

Pockets

9 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1048	0.87	0.88	79	empty
2	1076	0.74	0.77	74	empty
3	158	0.49	0.77	35	empty
4	133	0.44	0.76	21	empty
5	157	0.43	0.75	22	empty

Interfaces

1 interface between chains.

A–B · 2333 Å² buried · 17 hydrogen bonds · protein-protein

Compared structures

6O6T · Crystal structure of Csm6 H132A mutant · the same entry in another collection · chain B against B, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B6YWC3
Elsewhere: RCSB PDB 6O6T · PDBe 6O6T · UniProt B6YWC3

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