MolNFT v1 · #158736 · protein

Crystal structure of the actin-binding domain of human alpha-actinin-4

6O31: “Crystal structure of the actin-binding domain of human alpha-actinin-4”. X-ray diffraction, 1 pocket (best druggability 0.41). MolNFT v1 #158736 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6O31
Type: protein
Length: 226 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Alpha-actinin-4
UniProt: B4E337
Pockets: 1 · best druggability 0.41

Structure

x-ray diffraction · 1 distinct chain · 62% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Alpha-actinin-4	protein	226	62% helix, 2% strand	B4E337

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	92	0.41	0.78	19	empty

Compared structures

6O31 · Crystal structure of the actin-binding domain of human alpha-actinin-4 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B4E337
Elsewhere: RCSB PDB 6O31 · PDBe 6O31 · UniProt B4E337

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