MolNFT v1 · #158703 · protein
Structure of PCW3 conjugation coupling protein tcpa monomeric form with ATP
6O1Y · DNA translocase coupling protein: “Structure of PCW3 conjugation coupling protein tcpa monomeric form with ATP”. X-ray diffraction, 2 ligands (ATP, BGC), 10 pockets (best druggability 0.76). MolNFT v1 #158703 on GenesisL1: 3D…
- PDB
- 6O1Y
- Type
- protein
- Length
- 708 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DNA translocase coupling protein
- UniProt
- Q1PLI0
- Ligands
- ATP, BGC
- Pockets
- 10 · best druggability 0.76
Structure
x-ray diffraction · 2 distinct chains · 36% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA translocase coupling protein | protein | 353 | 38% helix, 23% strand | Q1PLI0 |
| B | DNA translocase coupling protein | protein | 355 | 35% helix, 23% strand | Q1PLI0 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
10 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 909 | 0.76 | 0.79 | 69 | ATP |
| 2 | 274 | 0.57 | 0.77 | 32 | empty |
| 3 | 163 | 0.48 | 0.77 | 25 | empty |
| 4 | 64 | 0.42 | 0.81 | 14 | empty |
| 5 | 108 | 0.41 | 0.77 | 27 | empty |
Interfaces
1 interface between chains.
- A–B · 1065 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
- 6O1Y · Structure of pCW3 conjugation coupling protein TcpA monomeric form with ATP · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q1PLI0
- Elsewhere: RCSB PDB 6O1Y · PDBe 6O1Y · UniProt Q1PLI0
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