MolNFT v1 · #158513 · protein

PYL10 bound to the selective agonist hexabactin

6NWB · Abscisic acid receptor PYL10: “PYL10 bound to the selective agonist hexabactin”. X-ray diffraction, 1 ligand (L6V), 1 pocket (best druggability 0.80). MolNFT v1 #158513 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6NWB
Type: protein
Length: 156 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Abscisic acid receptor PYL10
UniProt: Q8H1R0
Ligands: L6V
Pockets: 1 · best druggability 0.80

Structure

x-ray diffraction · 1 distinct chain · 26% helix, 41% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Abscisic acid receptor PYL10	protein	156	26% helix, 41% strand	Q8H1R0

Ligands and binding sites

L6V · N-{[(4-cyanophenyl)methyl]sulfonyl}-1-(thiophen-3-yl) cyclohexane-1-carboxamide · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	335	0.80	0.90	42	L6V

Compared structures

6NWB · PYL10 bound to the selective agonist hexabactin · the same entry in another collection · chain A against A, TM-score 1.00
Q8H1R0 · AlphaFold monomer V2.0 prediction for abscisic acid receptor PYL10 (Q8H1R0) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8H1R0
Elsewhere: RCSB PDB 6NWB · PDBe 6NWB · UniProt Q8H1R0

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