MolNFT v1 · #158442 · protein
2.1 a resolution structure of the musashi-2 (MSI2) RNA recognition motif 1 (RRM1) domain
6NTY · RNA-binding protein musashi homolog 2: “2.1 a resolution structure of the musashi-2 (MSI2) RNA recognition motif 1 (RRM1) domain”. X-ray diffraction, 1 ligand (PO4), 1 pocket (best druggability 0.48). MolNFT v1 #158442 on GenesisL1…
- PDB
- 6NTY
- Type
- protein
- Length
- 162 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RNA-binding protein musashi homolog 2
- UniProt
- Q96DH6
- Ligands
- PO4
- Pockets
- 1 · best druggability 0.48
Structure
x-ray diffraction · 2 distinct chains · 22% helix, 38% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RNA-binding protein musashi homolog 2 | protein | 82 | 22% helix, 38% strand | Q96DH6 |
| B | RNA-binding protein musashi homolog 2 | protein | 80 | 21% helix, 39% strand | Q96DH6 |
Ligands and binding sites
- PO4 · Phosphate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 182 | 0.48 | 0.75 | 27 | empty |
Interfaces
1 interface between chains.
- A–B · 750 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
- 6NTY · 2.1 A resolution structure of the Musashi-2 (Msi2) RNA recognition motif 1 (RRM1) domain · the same entry in another collection · chain A against A, TM-score 1.00
- Q96DH6 · AlphaFold monomer V2.0 prediction for RNA-binding protein musashi homolog 2 (Q96DH6) · a predicted model of the same protein · chain A against A, TM-score 0.89
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96DH6
- Elsewhere: RCSB PDB 6NTY · PDBe 6NTY · UniProt Q96DH6
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