MolNFT v1 · #157909 · protein

Outer membrane cytochrome S filament from geobacter sulfurreducens

6NEF · C-type cytochrome omcs: “Outer membrane cytochrome S filament from geobacter sulfurreducens”. Electron microscopy, 2 ligands (HEC, MG), 2 pockets (best druggability 0.85). MolNFT v1 #157909 on GenesisL1: 3D structure, binding sites…

PDB: 6NEF
Type: protein
Length: 407 residues
Chains: 1
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: C-type cytochrome omcs
UniProt: Q74A86
Ligands: HEC, MG
Pockets: 2 · best druggability 0.85

Structure

electron microscopy · 1 distinct chain · 12% helix, 6% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	C-type cytochrome omcs	protein	407	12% helix, 6% strand	Q74A86

Ligands and binding sites

HEC · Heme C · ligand · 6 copies · chains A
MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1182	0.85	0.86	112	HEC, MG
2	171	0.55	0.80	26	empty

Modifications

Observed in the structure: 6 cofactor (heme c attachment).

Compared structures

6NEF · Outer Membrane Cytochrome S Filament from Geobacter Sulfurreducens · the same entry in another collection · chain A against A, TM-score 1.00
Q74A86 · AlphaFold monomer V2.0 prediction for C-type cytochrome omcs (Q74A86) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q74A86
Elsewhere: RCSB PDB 6NEF · PDBe 6NEF · UniProt Q74A86

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.