MolNFT v1 · #157857 · protein
Interleukin-37 residues 53-206- dimer
6NCU: “Interleukin-37 residues 53-206- dimer”. X-ray diffraction, 3 pockets (best druggability 0.56). MolNFT v1 #157857 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6NCU
- Type
- protein
- Length
- 304 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Interleukin-37
- UniProt
- Q9NZH6
- Pockets
- 3 · best druggability 0.56
Structure
x-ray diffraction · 2 distinct chains · 7% helix, 41% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Interleukin-37 | protein | 150 | 4% helix, 39% strand | Q9NZH6 |
| B | Interleukin-37 | protein | 154 | 9% helix, 43% strand | Q9NZH6 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 224 | 0.56 | 0.78 | 31 | empty |
| 2 | 78 | 0.39 | 0.78 | 18 | empty |
| 3 | 59 | 0.34 | 0.77 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 208 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9NZH6
- Elsewhere: RCSB PDB 6NCU · PDBe 6NCU · UniProt Q9NZH6
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