MolNFT v1 · #157690 · protein
Structure of the human JAK1 kinase domain with compound 39
6N7A: “Structure of the human JAK1 kinase domain with compound 39”. X-ray diffraction, 1 ligand (KEV). MolNFT v1 #157690 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6N7A
- Type
- protein
- Length
- 572 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P23458
- Ligands
- KEV
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 278 | — | P23458 |
| B | — | protein | 294 | — | P23458 |
Ligands and binding sites
- KEV · N-[3-(5-chloro-2-methoxyphenyl)-1-methyl-1H-pyrazol-4-yl]-2-methyl-2H-pyrazolo[4,3-c]pyridine-7-carboxamide · ligand · 2 copies · chains A, B
- GOL · Glycerol · additive · 3 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6N7A · Structure of the human JAK1 kinase domain with compound 39 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P23458
- Elsewhere: RCSB PDB 6N7A · PDBe 6N7A · UniProt P23458
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