MolNFT v1 · #157515 · protein
Structure of wild-type CAO1
6N21 · Carotenoid oxygenase: “Structure of wild-type CAO1”. X-ray diffraction, 2 ligands (FE2, CL), 20 pockets (best druggability 0.84). MolNFT v1 #157515 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6N21
- Type
- protein
- Length
- 1,988 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Carotenoid oxygenase
- UniProt
- A0A0B0DIC8
- Ligands
- FE2, CL
- Pockets
- 20 · best druggability 0.84
Structure
x-ray diffraction · 1 distinct chain · 8% helix, 38% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | Carotenoid oxygenase | protein | 497 | 8% helix, 38% strand | A0A0B0DIC8 |
Ligands and binding sites
- FE2 · Fe (II) ion · metal · 4 copies · chains A, B, C, D
- CL · Chloride ion · ion · 4 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
20 pockets found on a 1 Å grid, 14 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 817 | 0.84 | 0.87 | 109 | empty |
| 2 | 421 | 0.84 | 0.92 | 70 | empty |
| 3 | 1044 | 0.84 | 0.85 | 122 | empty |
| 4 | 554 | 0.83 | 0.89 | 79 | empty |
| 5 | 266 | 0.83 | 0.95 | 56 | empty |
Interfaces
4 interfaces between chains.
- B–D · 1524 Ų buried · 35 hydrogen bonds · protein-protein
- A–C · 1508 Ų buried · 34 hydrogen bonds · protein-protein
- B–C · 402 Ų buried · 3 hydrogen bonds · protein-protein
- A–D · 366 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
- 6N21 · Structure of wild-type CAO1 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0B0DIC8
- Elsewhere: RCSB PDB 6N21 · PDBe 6N21 · UniProt A0A0B0DIC8
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.