MolNFT v1 · #157003 · protein

Crystal structure of X. citri phosphoglucomutase in complex with glucopyranosyl-1-methyl-phosphonic acid

6MLH: “Crystal structure of X. citri phosphoglucomutase in complex with glucopyranosyl-1-methyl-phosphonic acid”. X-ray diffraction, 2 ligands (GPM, MG), 3 pockets (best druggability 0.73). MolNFT v1 #157003 on GenesisL1: 3D structure…

PDB: 6MLH
Type: protein
Length: 448 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Phosphoglucomutase
UniProt: Q8PGN7
Ligands: GPM, MG
Pockets: 3 · best druggability 0.73

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Phosphoglucomutase	protein	448	41% helix, 21% strand	Q8PGN7

Ligands and binding sites

GPM · (1S)-1,5-anhydro-1-(phosphonomethyl)-D-glucitol · ligand · chains A
MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	526	0.73	0.82	60	GPM
2	61	0.32	0.76	14	empty
3	54	0.27	0.74	15	empty

Modifications

Observed in the structure: 1 modified (phosphorylation).

Compared structures

6MLH · Crystal structure of X. citri phosphoglucomutase in complex with… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8PGN7
Elsewhere: RCSB PDB 6MLH · PDBe 6MLH · UniProt Q8PGN7

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