MolNFT v1 · #156924 · protein

Structure of candida glabrata CSM1:MAM1 complex

6MJ8 · Monopolin complex subunit CSM1: “Structure of candida glabrata CSM1:MAM1 complex”. X-ray diffraction, 1 pocket (best druggability 0.63). MolNFT v1 #156924 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6MJ8
Type: protein
Length: 238 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Monopolin complex subunit CSM1; MAM1
UniProt: A0A0W0CH22, Q6FTD4
Pockets: 1 · best druggability 0.63

Structure

x-ray diffraction · 2 distinct chains · 43% helix, 29% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Monopolin complex subunit CSM1	protein	99	41% helix, 34% strand	A0A0W0CH22
C, D	MAM1	protein	20	50% helix, 0% strand	Q6FTD4

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	354	0.63	0.79	47	empty

Interfaces

5 interfaces between chains.

A–B · 1174 Å² buried · 4 hydrogen bonds · protein-protein
B–C · 815 Å² buried · 8 hydrogen bonds · protein-protein
A–D · 806 Å² buried · 10 hydrogen bonds · protein-protein
A–C · 155 Å² buried · 0 hydrogen bonds · protein-protein
B–D · 147 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

6MJ8 · Structure of Candida glabrata Csm1:Mam1 complex · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A0W0CH22
Every structure of UniProt Q6FTD4
Elsewhere: RCSB PDB 6MJ8 · PDBe 6MJ8 · UniProt A0A0W0CH22 · UniProt Q6FTD4

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