MolNFT v1 · #156815 · protein

Crystal structure of carbon-nitrogen hydrolase from helicobacter pylori G27

6MG6: “Crystal structure of carbon-nitrogen hydrolase from helicobacter pylori G27”. X-ray diffraction, 1 ligand (SO4), 5 pockets (best druggability 0.75). MolNFT v1 #156815 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6MG6
Type: protein
Length: 1,172 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Carbon-nitrogen hydrolase
UniProt: B5Z7B9
Ligands: SO4
Pockets: 5 · best druggability 0.75

Structure

x-ray diffraction · 3 distinct chains · 35% helix, 28% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Carbon-nitrogen hydrolase	protein	294	35% helix, 28% strand	B5Z7B9
B, C	Carbon-nitrogen hydrolase	protein	293	35% helix, 28% strand	B5Z7B9
D	Carbon-nitrogen hydrolase	protein	292	36% helix, 28% strand	B5Z7B9

Ligands and binding sites

SO4 · Sulfate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	270	0.75	0.89	43	empty
2	408	0.69	0.81	55	empty
3	331	0.67	0.81	33	empty
4	206	0.64	0.83	28	empty
5	313	0.63	0.79	29	empty

Interfaces

6 interfaces between chains.

A–B · 2783 Å² buried · 50 hydrogen bonds · protein-protein
C–D · 2412 Å² buried · 43 hydrogen bonds · protein-protein
B–C · 741 Å² buried · 10 hydrogen bonds · protein-protein
B–D · 535 Å² buried · 10 hydrogen bonds · protein-protein
A–C · 490 Å² buried · 7 hydrogen bonds · protein-protein

Compared structures

6MG6 · Crystal structure of carbon-nitrogen hydrolase from Helicobacter pylori G27 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B5Z7B9
Elsewhere: RCSB PDB 6MG6 · PDBe 6MG6 · UniProt B5Z7B9

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.