MolNFT v1 · #156783 · protein

Fragment of human fibronectin containing the 4TH-7TH type III domains

6MFA: “Fragment of human fibronectin containing the 4TH-7TH type III domains”. X-ray diffraction, 4 pockets (best druggability 0.55). MolNFT v1 #156783 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6MFA
Type: protein
Length: 363 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Fibronectin
UniProt: P02751
Pockets: 4 · best druggability 0.55

Structure

x-ray diffraction · 1 distinct chain · 0% helix, 52% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Fibronectin	protein	363	0% helix, 52% strand	P02751

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	292	0.55	0.76	39	empty
2	136	0.44	0.77	26	empty
3	67	0.41	0.80	21	empty
4	56	0.26	0.73	22	empty

Compared structures

6MFA · Fragment of human fibronectin containing the 4th-7th type III domains · the same entry in another collection · chain A against A, TM-score 1.00
P02751 · AlphaFold monomer V2.0 prediction for fibronectin (P02751) · a predicted model of the same protein · chain A against A, TM-score 0.57

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P02751
Elsewhere: RCSB PDB 6MFA · PDBe 6MFA · UniProt P02751

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